Robust Self-Replication
05-25-12
Erik Winfree, Professor of Computer Science, Computation and Neural Systems, and Bioengineering, and colleagues including Caltech alumnae Rebecca Schulman, have created a new system to copy sequence information. In their approach, tiny DNA tile crystals consisting of many copies of a piece of information are first grown, then broken into a few pieces by mechanically-induced scission, or force. The new crystal bits contain all the information needed to keep copying the sequence. Each piece then begins to replicate its information and grow until broken apart again—without the help of enzymes, an essential ingredient in biological sequence replication. [Caltech Press Release]
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Professor Siapas Receives NIH Pioneer Award
09-22-11
Thanos Siapas, Professor of Computation and Neural Systems, has received a National Institutes of Health (NIH) Pioneer Award. He plans to use the award to develop neural probes for large-scale recordings of brain activity. "Brain functions such as perception, learning, and memory arise from the coordinated activation of billions of neurons distributed throughout the brain," Siapas says. "While we know a lot about the properties of individual neurons, much less is known about how assemblies of neurons interact to perform computations. Our goal is to develop large-scale, multielectrode arrays that will enable the monitoring of many neurons simultaneously across different brain areas. We hope that such arrays will expose new fundamental insights into brain activity, and will find application in the study of animal models of brain disorders." [Caltech Press Release]
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