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Seeing More with a Needle-Shaped Laser

12-02-22

Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering; Andrew and Peggy Cherng Medical Engineering Leadership Chair; Executive Officer for Medical Engineering, and his research team show how they developed a new variant of photoacoustic microscopy (PAM) called needle-shaped beam photoacoustic microscopy (NB-PAM). NB-PAM has a depth of field nearly 14 times greater than what was achievable before. [Caltech story]

Tags: EE research highlights MedE Lihong Wang Rui Cao

Electronic/Photonic Chip Sandwich Pushes Boundaries of Computing and Data Transmission Efficiency

11-17-22

Engineers at Caltech and the University of Southampton in England have collaboratively designed an electronics chip integrated with a photonics chip (which uses light to transfer data)—creating a cohesive final product capable of transmitting information at ultrahigh speed while generating minimal heat. [Caltech story]

Tags: EE research highlights Azita Emami Minwo Wang Arian Hashemi Talkhooncheh

High-speed Camera Captures Signals Traveling Through Nerve Cells

10-07-22

Scientists have developed a new ultrafast camera that can record footage of impulses as they travel through nerve cells. The camera technology, known as differentially enhanced compressed ultrafast photography (Diff-CUP), was developed in the lab of Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering; Andrew and Peggy Cherng Medical Engineering Leadership Chair; Executive Officer for Medical Engineering. "Seeing nerve signals is fundamental to our scientific understanding but has not yet been achieved owing to the lack of speed and sensitivity provided by existing imaging methods," Wang says. [Caltech story]

Tags: EE research highlights MedE Lihong Wang Yide Zhang Binglin Shen Tong Wu Jerry Zhao Joseph Jing Peng Wang Kanomi Sasaki-Capela William Dunphy David Garrett Konstantin Maslov Weiwei Wang

Laser Light Offers New Tool for Treating Bone Cancer

09-20-22

Of the many ways to treat cancer, the oldest, and maybe most tried and true, is surgery. The goal is to remove all of the cancerous tissue while preserving as much of the surrounding healthy material as possible. "It's very hard to grow bone, so if you cut out bone, you basically lose it," says Lihong Wang, Bren Professor of Medical Engineering and Electrical Engineering; Andrew and Peggy Cherng Medical Engineering Leadership Chair; Executive Officer for Medical Engineering. A new diagnostic imaging technology developed by researchers at Caltech is offering surgeons the ability to make cuts 10 times more precisely, allowing them to preserve as much as 1,000 times more healthy tissue and to give patients easier recoveries. [Caltech story]

Tags: EE research highlights MedE Lihong Wang Rui Cao Samuel Davis Yilin Luo Yide Zhang

New Photonic Chip "Squeezes" More out of Light

09-15-22

Electronic computing and communications have come a very long way since the days of radio telegraphy and vacuum tubes, with consumer devices now containing levels of processing power and memory that would be unimaginable just a few decades ago. "The quality of the quantum states we have achieved surpasses the requirements for quantum information processing, which used to be the territory of bulky experimental setups," says Alireza Marandi, Assistant Professor of Electrical Engineering and Applied Physics. [Caltech story]

Tags: APhMS EE research highlights Alireza Marandi

Ask a Caltech Expert: Yaser Abu-Mostafa on AI and Finance

09-15-22

Can AI Predict Economic Downturns? There has been a symbiotic relationship between financial institutions and the artificial intelligence community since the 1980s. That's when the field of neural networks started in earnest. Although there was lots of activity, we can see in hindsight that neural networks did not reach their full potential owing to the lack of computational resources and lack of abundant data. [Caltech story]

Tags: EE research highlights Yaser Abu-Mostafa

New Research "UNCOVERS" Hidden Objects in High Resolution

08-11-22

Imagine driving home after a long day at work. Suddenly, a car careens out of an obscured side street and turns right in front of you. Luckily, your autonomous car saw this vehicle long before it came within your line of sight and slowed to avoid a crash. This might seem like magic, but a novel technique developed in the laboratory of Changhuei Yang, Thomas G. Myers Professor of Electrical Engineering, Bioengineering, and Medical Engineering; Investigator, Heritage Medical Research Institute, could bring it closer to a reality. "We can see all the traffic on the crossroads with this method. This might help the cars to foresee the potential danger that one is not able to see directly." explains electrical engineering graduate student Ruizhi Cao. [Caltech story]

Tags: EE research highlights Changhuei Yang MedE Ruizhi Cao

New Optical Switch Could Lead to Ultrafast All-Optical Signal Processing

07-30-22

One of the major limitations of optics-based systems at present is that, at a certain point, they still need to have electronics-based transistors to efficiently process the data. Now, a team led by Alireza Marandi, Assistant Professor of Electrical Engineering and Applied Physics, has created an all-optical switch. Such a switch could eventually enable data processing using photons. Device nanofabrication was performed at the Kavli Nanoscience Institute (KNI) at Caltech. [Caltech story]

Tags: research highlights KNI Alireza Marandi Rajveer Nehra Saman Jahani Luis Ledezma Arkadev Roy Qiushi Guo Ryoto Sekine Robert Gray

Nanofabrication Courses Let Caltech Undergraduates Get Hands-on at the Smallest Scales

05-27-22

The course combines topical lectures that give the students a preview of what they will be doing in the cleanroom along with hands-on practical training. Both components are conducted as a team effort between Scherer and the KNI technical staff. The first two lectures of the term were presented by KNI’s microscopist, Dr. Annalena Wolff, who lectured on scanning electron and focused ion beam microscopy. Additional lectures were presented by KNI’s Associate Director of Technical Operations, Dr. Guy DeRose, on electron beam lithography.

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Tags: APhMS EE research highlights MedE Axel Scherer KNI Changsoon Choi Paromita Mitchell Annalena Wolff Guy DeRose Bert Mendoza Alex Wertheim Kelly McKenzie

Researchers Help Generate First Image of Black Hole at the Center of Our Galaxy

05-12-22

A multi-institution collaboration that includes a Caltech-led imaging team has generated the first image of the supermassive black hole at the center of the Milky Way galaxy. This result provides conclusive evidence that the body, known as Sagittarius A* (Sgr A*, pronounced "sadge-ay-star"), is indeed a black hole and yields valuable clues about the workings of such massive objects, which are thought to reside at the center of most galaxies. "We not only recovered an image of Sgr A*, but also characterized the uncertainty of features in the image," says He Sun. "This analysis helped the team deliver scientific results with some guarantees." [Caltech story]

Tags: EE research highlights CMS Katie Bouman He Sun Junhan Kim Aviad Levis