Largest Biochemical Circuit Built Out of Small Synthetic DNA Molecules
Lulu Qian, Senior Postdoctoral Scholar in Bioengineering, and colleagues including Erik Winfree, Professor of Computer Science, Computation and Neural Systems, and Bioengineering, have built the most complex biochemical circuit ever created from scratch made with DNA-based devices in a test tube that are analogous to the electronic transistors on a computer chip."We're trying to borrow the ideas that have had huge success in the electronic world, such as abstract representations of computing operations, programming languages, and compilers, and apply them to the biomolecular world," says Dr. Qian. [Caltech Press Release]
Stimulating Electrode Array Assists Paraplegic Man to Stand and Move Legs Voluntarily
Joel W. Burdick, Professor of Mechanical Engineering and Bioengineering, and colleagues including Yu-Chong Tai, Professor of Electrical Engineering and Mechanical Engineering, have used a stimulating electrode array to assist a paralyzed man to stand, step on a treadmill with assistance, and, over time, to regain voluntary movements of his limbs. Using a combination of experimentation, computational models of the array and spinal cord, and machine-learning algorithms, Professor Burdick and his colleagues are now trying to optimize the stimulation pattern to achieve the best effects, and to improve the design of the electrode array. Further advances in the technology should lead to better control of the stepping and standing processes.
Amnon Yariv Awarded National Medal of Science
Amnon Yariv, Martin and Eileen Summerfield Professor of Applied Physics and Professor of Electrical Engineering, has received one of the highest honors bestowed by the United States government on scientists, and engineers. He is a recipient of the National Medal of Science. Professor Yariv's research group has pioneered the field of optoelectronics. Many innovations such as distributed Feedback (DFB) Semiconductor Lasers, Integrated Optoelectronic Circuits, Optical Phase Conjugation, External Cavity Tunable Semiconductor Lasers, Quantum Well Infrared Photodetectors (QWIP's), and all-fiber add/drop filters have found their beginnings in his research group. Currently, his group’s research aims at developing the new technologies that will be mandated by the seemingly endless appetite for optical bandwidth. Specifically, they are working at extending, to the field of laser optics, some key ideas that form the foundation of the microwaves and the radio frequencies fields. [Caltech Press Release], [White House Press Release] [Watch the White House Cermony]
Jehoshua Bruck Receives IEEE Best Paper Award
Jehoshua Bruck, Gordon and Betty Moore Professor of Computation and Neural Systems and Electrical Engineering, and colleagues' paper entitled Rank Modulation for Flash Memories has received the Institute of Electrical and Electronics Engineers (IEEE) Best Paper Award in Signal Processing and Coding for Data Storage. Rank modulation is a novel data representation scheme which the group has developed for multilevel flash memory cells. The idea is that a set of cells stores information in the permutation induced by the relative charge levels of the individual cells. As opposed to iterative (and slow) programming in current technology, rank modulation allows fast programming that is based on push-to-the-top operations, namely, raising the charge level of a single cell to be the highest one. [pdf] [Patent]