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Professor Winfree Elected to American Association for the Advancement of Science

12-02-15

Erik Winfree, Professor of Computer Science, Computation and Neural Systems, and Bioengineering, has been elected as a Fellow of the American Association for the Advancement of Science (AAAS) which is the world's largest general scientific society. Professor Winfree was recognized for his "foundational contributions to biomolecular computing and molecular programming." [Caltech story] [ENGenious feature]

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Robust Self-Replication

05-25-12

Erik Winfree, Professor of Computer Science, Computation and Neural Systems, and Bioengineering, and colleagues including Caltech alumnae Rebecca Schulman, have created a new system to copy sequence information. In their approach, tiny DNA tile crystals consisting of many copies of a piece of information are first grown, then broken into a few pieces by mechanically-induced scission, or force. The new crystal bits contain all the information needed to keep copying the sequence. Each piece then begins to replicate its information and grow until broken apart again—without the help of enzymes, an essential ingredient in biological sequence replication. [Caltech Press Release]

Tags: EE research highlights health CMS Erik Winfree Rebecca Schulman

DNA Robotics Research Earns Undergrads a Gold Prize

11-21-11

Undergraduate students Zibo Chen, Shayan Doroudi, Yae Lim Lee, Gregory Izatt, and Sarah Wittman have won a gold award at the 2011 International Bio-Molecular Design Competition (BIOMOD). BIOMOD is a competition for undergraduate teams who design research to address the control of biomolecules on the nanometer scale. The Caltech team's challenge was to make a synthetic DNA robot that has the ability to take a random walk —instead of walking on set path or track—on a two-dimensional origami surface that was also made out of DNA. The team is mentored by Professor Erik Winfree and sponsored by the Molecular Programming Project. [Caltech Feature] [Video of Project]

Tags: EE research highlights health CMS Erik Winfree Zibo Chen Shayan Doroudi Yae Lim Lee Gregory Izatt Sarah Wittman

First Artificial Neural Network Created Out of DNA

07-21-11

Lulu Qian, Senior Postdoctoral Scholar in Bioengineering; Erik Winfree, Professor of Computer Science, Computation and Neural Systems, and Bioengineering; and Jehoshua (Shuki) Bruck, Gordon and Betty Moore Professor of Computation and Neural Systems and Electrical Engineering, are the first to have made an artificial neural network out of DNA, creating a circuit of interacting molecules that can recall memories based on incomplete patterns, just as a brain can. [Caltech Press Release]

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Largest Biochemical Circuit Built Out of Small Synthetic DNA Molecules

06-02-11

Lulu Qian, Senior Postdoctoral Scholar in Bioengineering, and colleagues including Erik Winfree, Professor of Computer Science, Computation and Neural Systems, and Bioengineering, have built the most complex biochemical circuit ever created from scratch made with DNA-based devices in a test tube that are analogous to the electronic transistors on a computer chip."We're trying to borrow the ideas that have had huge success in the electronic world, such as abstract representations of computing operations, programming languages, and compilers, and apply them to the biomolecular world," says Dr. Qian. [Caltech Press Release]

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Erik Winfree Featured in Discover

08-18-09

The molecular computational research of Erik Winfree, Associate Professor of Computer Science, Computation and Neural Systems, and Bioengineering, focuses on understanding how chemical systems can perform information processing and how to program a set of molecules to carry out instructions. This exciting research was recently featured in Discover. [Discover Interview]

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